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. 2015 Nov 7;17:314. doi: 10.1186/s13075-015-0828-6

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© Hayashi et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — p21 levels influence the number of p-STAT3-positive cells in DMM mice. Cartilage tissue samples were collected from the right knee (sham or DMM surgery) of (a) p21^+/+ (sham), (b) p21^−/− (sham), (c) p21^+/+ (DMM), and (d) p21^−/− (DMM) mice. e Percentages of pSTAT3-positive stained cells (number of positive cells/number of total cells) with 95 % CI. The sections are stained for p-STAT3 antibody and counterstained with methyl green. Six mice were analyzed for each of the following groups: p21^+/+ sham, p21^+/+ DMM, p21^−/− sham, and p21^−/− DMM. CI confidence interval, DMM destabilization of the medial meniscus, p-STAT3 phosphorylated signal transducer and activator of transcription 3