Table 1.
Characteristics of the three study groups
| <3 h | 3–9 h | >9 h | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | n | Mean | SD | Median [IQR] | n | Mean | SD | Median [IQR] | n | Mean | SD | Median [IQR] | p-Value | |
| Age | 76 | 25 | 59,64 | 18,775 | 63 [50, 74] | 36 | 64,36 | 14,934 | 65 [56.25;76.5] | 15 | 68,8 | 14,586 | 69 [61;80] | 0,205 |
| Length of hospital stay | 76 | 25 | 20,64 | 14,731 | 22 [10, 28] | 36 | 28,75 | 32,056 | 17,5 [11;29] | 15 | 20,27 | 14,235 | 16 [11;27] | 0,921 |
| Duration of surgery (minutes) | 76 | 25 | 135,2 | 73,005 | 112 [97, 165.5] | 36 | 126,58 | 68,393 | 112,5 [70;170.25] | 15 | 127,07 | 47,596 | 135 [70; 160] | 0,744 |
| Ventilatory time (hours) | 76 | 25 | 29,524 | 51,3765 | 6,2 [0.5, 19.2] | 36 | 228,253 | 9,9 [5.175; 148.75] | 15 | 105,94 | 186,3957 | 7,7 [3.9;276] | 0,141 | |
| Katecholamins (within 24 h) | 76 | 25 | 7102,32 | 15541,449 | 450 [0, 9330] | 36 | 31294,5 | 80932,459 | 1911 [0; 9700] | 15 | 4570,8 | 8733,606 | 0 [0; 2340] | 0,604 |
| Bikarbonate | 76 | 25 | 84 | 123,929 | 0 [0, 155] | 36 | 65,56 | 91,634 | 50 [0; 100] | 15 | 40 | 54,116 | 0 [0;100] | 0,656 |
| Kristalloids | 76 | 25 | 2876 | 1416,945 | 2600 [1600, 4125] | 36 | 2564,17 | 1364,581 | 2525 [1562.5; 31^37.5] | 15 | 1990 | 978,373 | 1800 [1500; 2100] | 0,184 |
| Kolloids | 76 | 25 | 854 | 1951,384 | 500 [0, 1000] | 36 | 326,39 | 421,813 | 0 [0; 500] | 15 | 400 | 430,946 | 500 [0; 500] | 0,13 |
| Substitution of erythrocyte concentrates | 76 | 25 | 276 | 465,725 | 0 [0, 1020] | 36 | 283,33 | 411,617 | 0 [0; 990] | 15 | 260 | 0 | 437,199 [0; 1200] | 0,839 |
| Thrombocyte concentrates | 76 | 25 | 20 | 70,711 | 0 | 36 | 20,83 | 71,088 | 0 | 15 | 33,33 | 129,099 | 0 | 1 |
| Fresh frozen plasma | 76 | 25 | 100 | 322,749 | 0 | 36 | 187,5 | 432,497 | 0 | 15 | 133,33 | 296,808 | 0 | 0,322 |
| Glucose substitution within24h | 76 | 25 | 15,2 | 76 | 0 | 36 | 15,2 | 76 | 0 | 15 | 40 | 129,835 | 0 | 0,987 |
| Bicarbonate substitution within 24 h | 76 | 25 | 70 | 119,024 | 0 [0, 100] | 36 | 48,53 | 101,865 | 0 | 15 | 53,33 | 104,312 | 0 [0; 50] | 0,335 |
| Kistralloid substitution within 24 h | 76 | 25 | 2990,8 | 2348,709 | 2800 [1720, 3700] | 36 | 3198,61 | 1712,078 | 2800 [2000; 4500] | 15 | 2536,67 | 1155,649 | 2250 [1700; 3000] | 0,79 |
| Kolloid substitution within 24 h | 76 | 25 | 380 | 505,8 | 0 [0, 500] | 36 | 328,57 | 404,076 | 0 [0; 500] | 15 | 833,33 | 1531,417 | 0 [0; 1000] | 0,869 |
| Erythrocyte concentrates within 24 h | 76 | 25 | 108 | 285,657 | 0 | 36 | 233,33 | 424,937 | 0 [0; 300] | 15 | 260 | 337,639 | 0 [0; 600] | 0,056 |
| Thrombocyte concentrates within 24 h | 76 | 25 | 12 | 60 | 0 | 36 | 12 | 60 | 0 | 15 | 8,33 | 50 | 0 | 0,604 |
| FFP within 24 h | 76 | 25 | 48 | 132,665 | 0 | 36 | 177,78 | 390,685 | 0 [0; 350] | 15 | 26,67 | 103,28 | 0 | 0,283 |
| SAPS_II score after source control | 76 | 25 | 42,36 | 15,508 | 43 [29.5, 50.5] | 36 | 44,28 | 15,161 | 46 [31.25; 55.75] | 15 | 41,53 | 13,674 | 38 [34; 46] | 0,894 |
| APACHE II score after soruce control | 76 | 25 | 21,08 | 8,026 | 21 [14, 26] | 36 | 21,86 | 6,69 | 21,5 [17.25; 26.5] | 15 | 19,87 | 5,718 | 20 [16; 25] | 0,79 |
| SOFA score after source control | 76 | 25 | 6,32 | 4,059 | 6 [3, 9.5] | 36 | 7,28 | 3,377 | 7 [5; 10] | 15 | 6,27 | 3,127 | 6 [4; 9] | 0,479 |
| Gastric reflux within 24 h (ml) | 76 | 25 | 166 | 225,074 | 30 [0, 300] | 36 | 266,94 | 436,347 | 100 [0; 400] | 15 | 163,33 | 227,272 | 80 [0; 250] | 0,57 |
FFP fresh frozen plasma, SAPS Simplified Acute Physiology Score, APACHE Acute Physiology and Chronic Health Evaluation II-score, SOFA Sequential Organ Failure Assessment score