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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Cancer Immunol Res. 2015 Jun 30;3(11):1248–1256. doi: 10.1158/2326-6066.CIR-15-0119

Figure 3.

Figure 3

Partial response in a patient with chordoma. A 47-year-old male was diagnosed in 2004 with a large sacral chordoma (12 cm). He underwent surgery followed by radiation with recurrent disease within 1 year. The patient subsequently underwent multiple surgical resections and further courses of radiation, with no response. He was treated with 30 and 36 Gy (in 3 fractions; 10 and 12 Gy fractions), to the anterior and posterior pelvic masses, respectively, about 3.5 months prior to enrollment. A and B, Baseline MRI with right anterior pelvic mass, and left posterior pelvic mass. C and D, After 8 doses of vaccine, both masses decreased in size, constituting a partial response. E and F, The patient had a continued response with a 42% decrease in overall size of tumors up to 9 months after the partial response.