Table 2.
Effect of zinc oxide nanoparticles and insulin on sperm analysis and serum testosterone level in streptozotocin-induced diabetic rat.
| Parameters | Control | Diabetic | Diabetic + ZnONPs | Diabetic + ZnONPs + insulin |
|---|---|---|---|---|
| Count (million/mL) | 108.3 ± 5.7a | 57.5 ± 4.5c | 93.5 ± 9.3b | 98.8 ± 3.8ab |
| Rapid motility (%) (grade a) | 44.45 ± 3.6a | 6 ± 0.05c | 37.1 ± 2.8b | 42 ± 4.4a |
| Slow motility (%) (grade b) | 13.55 ± 0.5b | 18.7 ± 2.6a | 15 ± 1.3b | 15 ± 0.8b |
| Nonprogressive motility (%) (grade c) | 22.4 ± 5.7 | 23 ± 2.2 | 23 ± 2.8 | 22 ± 1.6 |
| Immotile sperm (%) (grade d) | 20 ± 1.6b | 53.3 ± 7a | 24.9 ± 2b | 21 ± 2b |
| Motility (%) | 80 ± 9.8a | 47.7 ± 4.9c | 75.1 ± 6.9b | 79 ± 6.8a |
| Serum testosterone (ng/dL) | 5.7 ± 1.6a | 2.6 ± 0.8b | 5 ± 1.6a | 6.2 ± 1.4a |
Each point represents the mean ± D from triplicate determinations (n = 10 rats per group). Means within the same row carrying different superscripts (a, b, and c) are significant at p < 0.05.