Table 1.
Name of cyclodextrin | Solubility (mg/mL) | Mol. Wt. (Da) |
---|---|---|
Natural cyclodextrins | ||
Alpha cyclodextrin | 145 | 972 |
Beta cyclodextrin | 18.5 | 1135 |
Gamma cyclodextrin | 232 | 1297 |
| ||
Chemically modified cyclodextrins | ||
Hydroxypropyl-β-cyclodextrin | ≥600 | 1400 |
Sulfobutyl ether-β-cyclodextrin | ≥500 | 2163 |
Randomly methylated-β-cyclodextrin | ≥500 | 1312 |
Hydroxypropyl-γ-cyclodextrin | ≥500 | 1576 |
| ||
Polymerized cyclodextrins | ||
Epichlorohydrin-β-cyclodextrin | >500 | 112000 |
Carboxy methyl epichlorohydrin beta cyclodextrin | >250 | 2000000–15000000 |