Table 2.
Epithelial-to-Mesenchymal Transition (EMT) related genes that are significantly upregulated after HEK293 cells exposed to IGROV1 cell-secreted exosomes.
| Fold change | Genes |
|---|---|
| 25.65 | TIMP1 |
| 10.95 | FOXC2 |
| 10.55 | NOTCH1 |
| 9.67 | PTP4A1 |
| 8.32 | GNG11 |
| 7.37 | SNAI1 |
| 7.33 | FGFBP1 |
| 7.13 | SOX10 |
| 6.58 | COL3A1 |
| 6.49 | JAG1 |
| 6.45 | WNT5A |
| 6.41 | SNAI3 |
| 6.38 | NODAL |
| 6.35 | CDH1 |
| 6.32 | IL1RN |
| 6.04 | TMEM132A |
| 5.7 | COL1A2 |
| 5.53 | GSC |
| 5.39 | MMP3 |
| 5.35 | ERBB3 |
| 5.32 | SNAI2 |
| 5.24 | BMP1 |
| 5.2 | KRT7 |
| 5.15 | MST1R |
| 5.13 | PTK2 |
| 4.82 | F11R |
| 4.78 | AHNAK |
| 4.49 | IGFBP4 |
| 4.29 | FZD7 |
| 4.28 | TWIST1 |
| 4.19 | ITGA5 |
| 4.14 | WNT5B |
| 4.12 | STAT3 |
| 4.09 | BMP7 |
| 4 | MMP9 |
| 3.95 | SPP1 |
| 3.86 | SPARC |
| 3.82 | SERPINE1 |
| 3.81 | ILK |
| 3.8 | PLEK2 |
| 3.37 | WNT11 |
| 3.25 | TMEFF1 |
| 3.22 | TGFB1 |
| 3.09 | TGFB3 |
| 3.03 | ZEB1 |