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. 2015 Oct 25;2015:895284. doi: 10.1155/2015/895284

Figure 4.

Figure 4

CRT prevents apoptosis among OGD-exposed SH-SY5Y cells and downregulates the activity of caspase-8 and caspase-3. SH-SY5Y cells were cultured in medium with or without 40 ng/mL CRT after OGD. (a1, 2) Apoptosis rate of OGD-exposed SH-SY5Y cells as detected by flow cytometry at 6 h after reperfusion and activity of (b) caspase-8 and (c) caspase-3 as detected using caspase activity assay kits at 3, 6, 12, and 24 h after reperfusion. Control: normal SH-SY5Y cells. ∗∗ P < 0.01, ∗∗∗ P < 0.0001 versus control and # P < 0.05 versus OGD group. n = 6 repeats.