Figure 5.
SP and PGP9.5 nerve fiber density in five different regions of epithelial damage. (A) SP is increased in the epithelium adjacent to denuded epithelium. In the highest exposure group, SP is also increased in the detaching epithelium. Air and 25-ppm exposure contained only intact epithelium. Insufficient data for significance of detaching epithelium in 249-ppm group. (B) PGP9.5 nerve fiber density. Insufficient data for attenuated epithelium in 249-ppm group. SP = substance P; PGP9.5 = protein gene product 9.5.
*Significantly greater than the control. §Significantly less than the control. p ≤ .05.