Skip to main content
. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: J Immunol. 2015 Oct 14;195(10):4685–4698. doi: 10.4049/jimmunol.1500806

Figure 2.

Figure 2

Transgenic ApoA-I expression reduces B cell activation and anti-ds DNA IgG autoantibodies in Sle123→ApoA-Itg mice. (A) Anti-dsDNA autoantibody levels in control (n=7), WT BMT control (n=7) and Sle123 BMT (n=10) animal groups. Ages of animals in weeks on y-axis. (B) Flow cytometric analysis of lymph node B220+ B lymphocyte activation (measured by CD69 expression) in 38 week old control (n=12–15), control WT BMT (n=10–12) and Sle123 BMT (n=12–15) mice. Reduced numbers of B cells and lower B cell activation in Sle123→ApoA-Itg mice. (All data mean ± SD, *p<0.05 by one way ANOVA within control, control WT BMT or Sle123 BMT groups, ‡p<0.05 by T test compared to control).