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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Surgery. 2015 Aug 18;158(6):1564–1572. doi: 10.1016/j.surg.2015.07.023

Figure 2. E-cadherin expression is strong, membranous, and ubiquitous in PanIN lesions regardless of age, diet, or PanIN stage.

Figure 2

Representative sections of IHC expression of E-Cadherin in mouse pancreata (age, diet): 20× magnification image of (A) 3-month, CD, (B) 3-month, HFCD, (C) 9-month, CD, and (D) 9-month, HFCD mice. (E) 40× magnification view of low-grade PanIN lesion in CD fed mouse, and (F) 40× magnification view of high-grade PanIN lesion in HFCD demonstrating similar E-cadherin staining pattern. 20× magnification images of (G) 3-month and (H) 9-month HFCD fed mice using isotype-matched control rabbit IgG demonstrating lack of nonspecific binding.