Skip to main content
. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: J Immunol. 2015 Oct 2;195(10):4730–4741. doi: 10.4049/jimmunol.1500438

Figure 5. Igλ usage is reduced in NOD mice, even in the absence of H chain usage bias.

Figure 5

B cell subsets were identified in freshly isolated bone marrow or spleen using flow cytometry as in Fig. 1D and the percentage of Igλ+ B cells was assessed in NOD or B6 mice, representative plots are shown in (A). The average Igλ % ± SD is shown for WT (B) or VH125Tg (C) B6 (black) or NOD (white) mice, n ≥ 6 8–12 week old mice per group, n ≥ 2 experiments. * p < 0.05, ** p < 0.001, *** p < 0.001, two-tailed t-test.