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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Psychoneuroendocrinology. 2015 Sep 7;62:252–264. doi: 10.1016/j.psyneuen.2015.08.025

Figure 2. Adolescent Stress and Periadolescent Fructose Affect Weight Gain and Blood Glucose.

Figure 2

a. The percent of weight gained during the mid-adolescent stressor (PND37-49) was reduced in the stress cohorts (p<0.05) and fructose-fed animals gained more weight during this period (p<0.05). b. The fructose diet also significantly increased fasting glucose during mid-adolescence (p<0.05) irrespective of stress history. c. Glucose administration in the glucose tolerance test raised blood glucose in both chow and fructose stress & non-stress groups (p<0.05) as expected. However, fructose diet exacerbated this effect and fructose-fed rats had significantly higher blood glucose in the glucose challenge than the standard chow fed rats (p<0.05). d. Only a main effect of glucose administration (p < 0.05) was observed in analysis of plasma insulin; neither fructose nor stress, nor an interaction of either with the other or with glucose altered plasma insulin. Data shown are mean ± SEM; different letters indicate significant differences (p < 0.05) as assessed by post-hoc testing. NS=Non-stressed; S=Stressed; C=Saline-injected control; G=Glucose-injected