Skip to main content
. 2015 Jul 21;6(23):19381–19392. doi: 10.18632/oncotarget.4574

Figure 1. The miR-17-92 cluster.

Figure 1

A. Genomic localization of the miR-17-92 cluster (MIR17HG). The two transcripts of the gene are reported in blue. The miRNAs belonging to the cluster are reported in red. The panel of the figure was created modifying the output of the UCSC genome browser. B. Structure of the miR-17-92 cluster (MIR17HG, located on chromosome 13) and of the two paralogs (located on chromosomes X and 7). Both paralogs contains homologous miRNAs to a subset of miR-17-92 components. C. miRNA families of the miR-17-92 cluster. Four separate miRNA families according to miRNA seed sequences have been defined: the miR-17, miR-18, miR-19 and miR-92 families. miR-17, miR-18 and miR-19 families are composed also by miRNAs belonging to the paralogs. Seed sequences are reported in bold.