Figure 6. Analysis of CAIX positive and CAIX negative cell lines on ability to promote tumour growth in vivo.

CAIX+ve and CAIX-ve cells derived from SW1222 cells were implanted at 1000 A. or 200 cells B. and growth monitored over time. C. CAIX knockdown reduced the growth rate of MDA-MB-468 xenografts. D. Q-PCR analysis of stem cells genes in shMDA-MB-468 and Empty Vector (EV) xenografts. Error bars represent the mean ± SD, *p < 0.05, n = 3.