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. 2015 May 8;6(23):19469–19482. doi: 10.18632/oncotarget.3625

Figure 6. Curcumin decreased VEGF secretion from tumor cells and prolonged survival time of tumor-bearing mice.

Figure 6

A. Plasma was prepared by centrifuging the peripheral blood in the presence of anticoagulant EDTA after animal sacrifice, then VEGF content was determined by ELISA; B. Condition medium of T241-VEGF after treated with curcumin for 8 hours was collected and content of VEGF was determined by ELISA; C. Cell viability of T241-VEGF after treated with curcumin for 12 hours; D. The percentage of survival animals in curcumin treatment group (treated with 5 mM curcumin solution, 100 μL per mouse) and control group is presented during a 14-day-treatment course. (**p < 0.01 vs control; ***p < 0.001 vs control)