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. 2015 Jun 17;6(23):19542–19551. doi: 10.18632/oncotarget.4295

Figure 2. The C228T mutation contributes to tumorigenesis of bladder cancer.

Figure 2

A. BCSCs(T228C) was constructed by a TALEN approach. 100 cells for each subpopulations were injected intradermally into NOD/SCID mice followed by observing tumor formation in mice. Xenograft tumors denote with arrowheads. B. NBBCs(C228T) was established by the same TALEN approach and tumor formation was detected as above. C. Tumor formation rates of subpopulation cells were presented. **p < 0.01.