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. 2015 Apr 17;6(23):19605–19618. doi: 10.18632/oncotarget.3747

Figure 1. TS induces EMT morphological change and enhances migratory and invasive capacities of normal human bronchial epithelial (NHBE) cells.

Figure 1

A. Effect of cigarette smoke extract (CSE) on cell viability of NHBE cells. NHBE cells were treated with various concentrations of CSE for 7 days and cell viability was measured by MTT assay. B. CSE induced morphological change from epithelial to spindle-like mesenchymal shape, as shown by morphological examination of NHBE cells following CSE treatment for 7 days. C. CSE enhanced migratory capacity of NHBE cells, as determined by transwell migration assay. D. CSE enhanced invasive capacity of NHBE cells, determined by transwell invasion assay. Data are expressed as mean ± SD. **P < 0.01, compared with control group.