Table 1. Enrichment of KEGG pathways among significantly up-regulated genes in spinal ependymomas.
| Pathway | N | FDR |
|---|---|---|
| Protein processing in endoplasmic reticulum | 28 | 5.44 × 10−06 |
| Tight junction | 21 | 4.06 × 10−04 |
| Nucleotide excision repair | 10 | 1.98 × 10−03 |
| Cell adhesion molecules (CAMs) | 19 | 2.01 × 10−03 |
| Pyrimidine metabolism | 15 | 3.25 × 10−03 |
| Pyruvate metabolism | 9 | 4.17 × 10−03 |
| RNA transport | 19 | 6.02 × 10−03 |
| Purine metabolism | 20 | 6.11 × 10−03 |
| PPAR signaling pathway | 11 | 1.69 × 10−02 |
| Proteasome | 8 | 1.70 × 10−02 |
| Adherens junction | 11 | 1.79 × 10−02 |
| Oxidative phosphorylation | 16 | 2.04 × 10−02 |
| Focal adhesion | 21 | 2.54 × 10−02 |
Enrichment P values for KEGG pathways were calculated using the Hyper-geometric test and corrected for multiple testing using Benjamini & Hoachberg method. The pathways with adjusted P values < 0.05 were selected. N: number of genes in the pathway; FDR: false discovery rate.