Table 3. Prioritization of Chromosome 22 genes by network and NF2 gene co-expression analyses.
Correlation with NF2 gene expression | ||||||
---|---|---|---|---|---|---|
Symbol | Gene name | Location | DAPPLE P value |
ES | SE | FDR |
EP300 | E1A binding protein p300 | 22q13.2 | 0.002 | 0.45 | 0.19 | 0.039 |
HIRA | Histone cell cycle regulator | 22q11.21 | 0.015 | 0.46 | 0.14 | 0.004 |
MN1 | Meningioma (disrupted in balanced translocation) 1 | 22q12.1 | 0.017 | 0.10 | 0.08 | 0.223 |
SGSM3 | Small G protein signaling modulator 3 | 22q13.1-q13.2 | 0.021 | 0.54 | 0.06 | 1.04 × 10−14 |
SUSD2 | Sushi domain containing 2 | 22q11-q12 | 0.023 | 0.21 | 0.06 | 0.004 |
SREBF2 | Sterol regulatory element binding transcription factor 2 | 22q13 | 0.025 | 0.52 | 0.06 | 1.20 × 10−13 |
RASD2 | RASD family, member 2 | 22q13.1 | 0.033 | 0.26 | 0.07 | 5.56 × 10−04 |
LZTR1 | Leucine-zipper-like transcription regulator 1 | 22q11.21 | 0.044 | 0.42 | 0.07 | 1.59 × 10−07 |