Table 3.
Medication information for study sample.
| SZP (n = 105) | PBP (n = 87) | SZAP (n = 72) | SZR (n = 82) | PBPR (n = 80) | SZAR (n = 71) | HC (n = 110) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
| No medication taken | 5 | 4.8 | 5 | 5.7 | 3 | 4.2 | 66 | 80.5 | 53 | 66.3 | 53 | 74.6 | 107 | 97.3 |
| Not on psychotropic medications | 8 | 7.6 | 23 | 26.4 | 10 | 13.9 | 80 | 97.6 | 78 | 97.5 | 2 | 2.8 | 0 | 0 |
| On more than one psychotropic medications | 12 | 11.4 | 2 | 2.3 | 5 | 6.9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Anticholinergic/antiparkinsonian | 19 | 18.1 | 6 | 6.9 | 9 | 12.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Antidepressant (any) | 38 | 36.2 | 39 | 44.8 | 42 | 58.3 | 8 | 9.8 | 23 | 28.8 | 12 | 16.9 | 3 | 2.7 |
| A. Tricyclic | 0 | 0 | 3 | 3.4 | 3 | 4.2 | 0 | 0 | 2 | 2 | 0 | 0 | ||
| B. MAO inhibitors | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| C. SSRI/SNRI | 29 | 27.6 | 22 | 25.3 | 30 | 41.6 | 7 | 8.5 | 18 | 22.5 | 9 | 12.7 | 2 | 1.8 |
| D. Miscellaneous | 15 | 14.3 | 23 | 26.4 | 22 | 30.6 | 1 | 1.2 | 5 | 6.3 | 2 | 2.8 | 2 | 1.8 |
| Antipsychotic (any) | 97 | 92.4 | 64 | 73.6 | 63 | 87.5 | 2 | 2.4 | 2 | 2.5 | 2 | 2.8 | 0 | 0 |
| A. First generation | 21 | 0.2 | 5 | 5.7 | 12 | 16.7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| B. Second generation | 88 | 83.8 | 61 | 70.1 | 55 | 76.4 | 2 | 2.4 | 2 | 2.5 | 0 | 0 | 0 | 0 |
| Anxiolytic/hypnotic | 21 | 0.2 | 22 | 25.3 | 25 | 34.7 | 9 | 11 | 7 | 8.8 | 5 | 7 | 1 | 0.9 |
| Mood stabilizer (any) | 22 | 21 | 63 | 72.4 | 44 | 61.1 | 0 | 0 | 3 | 3.8 | 5 | 7 | 0 | 0 |
| A. Lithium | 7 | 6.7 | 25 | 28.7 | 12 | 16.7 | 0 | 0 | 1 | 1.3 | 0 | 0 | 0 | 0 |
| B. Anticonvulsants | 17 | 16.2 | 48 | 55.2 | 35 | 48.6 | 0 | 0 | 2 | 2.5 | 5 | 7 | 0 | 0 |
| Miscellaneous, centrally active | 2 | 1.9 | 5 | 5.7 | 5 | 6.9 | 0 | 0 | 0 | 0 | 1 | 1.4 | 0 | 0 |
| Stimulants | 3 | 2.9 | 10 | 11.4 | 2 | 2.8 | 1 | 1.2 | 2 | 2.5 | 2 | 2.8 | 0 | 0 |
HC, healthy comparison; PBP, psychotic bipolar disorder; PBPR, relatives of psychotic bipolar probands; SZ, schizophrenia; SZA, schizoaffective; SZAR, relatives of schizoaffective probands; SZR, relatives of schizophrenia probands.