Table 1.
Differences between outer and inner oscillatory activity in the rd retina (for detailed information, see text).
| Outer rd retina | Inner rd retina | |
|---|---|---|
| Degenerative re-modeling of synaptic contacts | Severe | None to minor (not enough data) |
| Trigger of synaptic activity | Synaptic remodeling | Intrinsic and/or lack of input from outer retina |
| Participating cell types | Cones, rod bipolar cells, horizontal cells (?) | Cone bipolar cells, AII amacrine cells, ganglion cells |
| Number of simultaneously oscillating cells | Clusters of up to 10 cells | Dozens of ganglion cells |
| Frequency of spontaneous events | Maximum ~3 Hz | ~10 Hz |
| Effect of GABA receptor antagonists | Decrease in activity | Increase in activity or no effect |