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. 2015 Sep 1;8(9):10002–10013.

Table 2.

Semi-quantitative analysis of histopathological changes in the lung tissues of severe falciparum malaria patients with non-PE and PE

Histopathological changes Grading score (mean ± SEM) P value

non-PE (n = 19) PE (n = 18)
PRBC sequestration 0.00 ± 0.00 0.39 ± 0.24 0.067
Alveolar hemorrhage 0.32 ± 0.17 1.56 ± 0.29 0.001*
Septal hemorrhage 2.21 ± 0.20 3.00 ± 0.28 0.014*
Aveolar edema 0.00 ± 0.00 2.72 ± 0.24 0.001*
Alveolar macrophage 1.95 ± 0.12 3.28 ± 0.16 0.001*
Leukocyte infiltration 1.89 ± 0.11 2.61 ± 0.16 0.001*
Septal thickening 0.05 ± 0.05 0.17 ± 0.12 0.500
Lung injury score 6.42 ± 0.41 13.72 ± 0.45 0.001*
*

Significant difference of P < 0.05, compared to non-PE group.