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Luteolin improves diabetes-induced deficit in mechanical, heat and cold sensation (n=10 in each group). Luteolin significantly increased mechanical withdrawal threshold (A), the paw withdrawal latency to heat (B) and cold stimuli (C) in diabetic rats. *P<0.05 for the comparison to the normal rats, #P<0.05 for the comparison to the saline-treated diabetic rats, $P<0.05 for the comparison to the diabetic rats treated with luteolin at 50 mg/kg.
