Table 1.
Correlation between RIT1 expression and clinicopathologic features in patients with endometrial cancer (EC)
| Expression of RIT1 | ||||
|---|---|---|---|---|
|
|
||||
| Total | Low (%) | High (%) | P value | |
| Age | ||||
| <45 | 24 | 14 (58.3) | 10 (41.7) | 0.299 |
| ≥45 | 233 | 110 (47.2) | 123 (52.8) | |
| Menopause | ||||
| Yes | 169 | 81 (47.9) | 88 (52.1) | 0.887 |
| No | 88 | 43 (48.9) | 45 (51.1) | |
| Pregnancy | ||||
| Yes | 13 | 8 (61.5) | 5 (38.5) | 0.325 |
| No | 224 | 116 (51.8) | 128 (58.2) | |
| Family history | ||||
| Yes | 17 | 5 (29.4) | 12 (70.6) | 0.108 |
| No | 240 | 119 (49.6) | 121 (50.4) | |
| Pathological type | ||||
| Adenocarcinoma | 233 | 118 (50.6) | 115 (49.4) | 0.017 |
| Squamous cell carcinoma, papillary serous carcinoma, and clear cell carcinoma | 24 | 6 (25.0) | 18 (75.0) | |
| Clinical Stage (FIGO) | ||||
| I | 216 | 114 (52.8) | 102 (47.2) | 0.001 |
| II | 19 | 7 (36.8) | 12 (63.2) | |
| III and IV | 22 | 3 (13.6) | 19 (86.4) | |
| Grade | ||||
| G1 | 144 | 79 (54.9) | 65 (45.1) | 0.042 |
| G2 | 78 | 33 (42.3) | 45 (57.7) | |
| G3 | 35 | 12 (34.3) | 23 (65.7) | |
| Vascular invasion | ||||
| Yes | 22 | 4 (18.2) | 18 (81.8) | 0.003 |
| No | 235 | 120 (51.1) | 115 (48.9) | |
| Lymphatic metastasis | ||||
| Yes | 14 | 3 (21.4) | 11 (78.6) | 0.053 |
| No | 243 | 121 (49.8) | 122 (50.2) | |
Note: Values in parentheses demonstrate percentage values. FIGO: International Federation of Gynecology and Obstertrics. The bold numbers present the P-values with significant differences.