Table 6.
Association between the BTNL2 SNPs in the dominant model and patient’s survival
| Overall survival | |||||||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| Characteristics | NYHA | Univariate survival analysis | Multivariate survival analysis* | ||||
|
|
|||||||
| HR | 95% CI | P | HR | 95% CI | P | ||
| SNP | |||||||
| rs3763313 | III | 0.555 | (0.121, 2.546) | 0.449 | 0.227 | (0.039, 1.334) | 0.101 |
| (AA/AC vs. CC) | IV | 0.280 | (0.108, 0.727) | 0.009 | 0.238 | (0.054, 1.054) | 0.059 |
| rs9268494 | III | 0.465 | (0.140, 1.549) | 0.212 | 0.152 | (0.021, 1.079) | 0.060 |
| (CC/CA vs. AA) | IV | 0.520 | (0.225, 1.201) | 0.126 | 0.727 | (0.285, 1.858) | 0.505 |
| rs9268492 | III | 0.538 | (0.118, 2.464) | 0.425 | 1.242 | (0.175, 8.793) | 0.828 |
| (CC/GC vs. GG) | IV | 1.140 | (0.423, 3.073) | 0.795 | 1.048 | (0.326, 3.369) | 0.937 |
| rs9268402 | III | 0.471 | (0.151, 1.467) | 0.194 | 0.700 | (0.203, 2.415) | 0.573 |
| (AA/GA vs. GG) | IV | 0.407 | (0.176, 0.944) | 0.029 | 0.241 | (0.089, 0.650) | 0.005 |
| Haplotype | |||||||
| C-C-A-T | I-IV | 0.282 | (0.087, 0.919) | 0.036 | 0.126 | (0.035, 0.457) | 0.002 |
HR, hazard ratio; CI, confidence interval.