Table 2.

Univariate and multivariate analysis of clinicopathological and E2F2 for overall and disease-free survival in NSCLC (n = 86)

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Overall survival
Age (< 49 vs. ≥ 49 years)	0.711 (0.392-1.290)	0.262
Gender (female vs. male)	0.962 (0.546-1.697)	0.895
Lymph node metastasis (yes vs. no)	1.053 (0.578-1.918)	0.865
Tumor size (< 4 vs. ≥ 4 cm)	0.460 (0.236-0.895)	0.022	0.452 (0.246-0.831)	0.011
Tumor recurrence (yes vs. no)	1.319 (0.701-2.482)	0.391
Tumor location	0.654 (0.368-1.161)	0.147
Stage (I-II vs. III-IV)	0.942 (0.535-1.660)	0.837
E2F2 expression (low vs. high)	0.407 (0.224-0.740)	0.003	0.490 (0.282-0.853)	0.012
Disease-free survival
Age (< 49 vs. ≥ 49 years)	0.719 (0.396-1.304)	0.278
Gender (female vs. male)	0.902 (0.511-1.592)	0.721
Lymph node metastasis (yes vs. no)	1.133 (0.624-2.057)	0.683
Tumor size (< 5 vs. ≥ 5 cm)	0.593 (0.307-1.147)	0.120
Tumor recurrence (yes vs. no)	1.174 (0.632-2.183)	0.611
Tumor location	0.794 (0.448-1.408)	0.431
Stage (I-II vs. III-IV)	0.870 (0.489-1.545)	0.633
E2F2 expression (low vs. high)	0.799 (0.472-1.351)	0.402