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. 2015 Sep 1;8(9):10595–10604.

Figure 2.

Figure 2

Overexpression of miR-10b inhibits cell proliferation, cell cycle, cell migration and invasion in 786-O and ACHN cells. The expression of miR-10b was significantly increased in 786-O (A) and ACHN (F) cells after transfecting with miR-10b lentivirus. Overexpression of miR-10b dramatically reduced cell growth in 786-O (B) and ACHN (G) cells. Overexpression of miR-10b arrested cell cycle at S phase in 786-O (C) and ACHN (H) cells, significantly inhibited cell migration in 786-O (D) and ACHN (I) cells, and repressed cell invasion in 786-O (E) and ACHN (J) cells. Data are presented by means ± s.d, *P<0.05, **P<0.01, ***P<0.001 vs. negative control (NC).