Figure 3.

TROP2 promotes cell proliferation in NPC cells. A. TROP2 expression was detected by real-time RT-PCR. Overexpression of TROP2 was observed in CNE-1 cells, while a reduction was exhibited after the cells transfected with anti-TROP2 SIRNA. B. Western blotting of TROP2 in CNE-1 cells was determined 48 hours post-transfection. C. Knock-down TROP2 reduced cell viability measuring by the MTT assay 24-72 hours after transfection. Each datum represents the mean fold change ± SE in triplicates.