Figure 1.

JMJD1A expression is upregulated in gastric cancer. (A) Representative photomicrographs showed JMJD1A expression, which was found to be localized in the nucleus (Scale bar, 50 μm). (B) Higher JMJD1A expression in gastric cancer samples in comparisons with matched adjacent non-tumor tissues. (C, D) Compared to gastric epithelial cell line GES-1, the five gastric cancer cell lines exhibited higher mRNA (C) and protein (D) expression levels of JMJD1A, and the MKN-45 cells exhibited relatively high levels in five cancer cell lines. (E, F) The expression of JMJD1A was increased in tissue with advanced stage as compared to early stage of gastric cancer (Scale bar, 20 μm).