Table 7.
Correlation of concomitant high expression of GPER1, EGFR and CXCR1 with the occurrence of FTC
| FTA n (%) | FTC n (%) | P value | |
|---|---|---|---|
| GPER1/EGFR | < 0.012a | ||
| Both GPER1/EGFR were low expression | 59 (83.1) | 12 (16.9) | |
| One of GPER1/EGFR was high expression | 63 (65.6) | 33 (34.4) | < 0.001b |
| Both GPER1/EGFR were high expression | 6 (9.0) | 61 (91.0) | |
| GPER1/CXCR1 | < 0.030a | ||
| Both GPER1/CXCR1 were low expression | 58 (81.7) | 13 (18.3) | |
| One of GPER1/CXCR1 was high expression | 66 (66.7) | 33 (33.3) | < 0.001b |
| Both GPER1/CXCR1 were high expression | 4 (6.2) | 60 (93.8) | |
| EGFR/CXCR1 | < 0.020a | ||
| Both EGFR/CXCR1 were low expression | 62 (81.6) | 14 (18.4) | |
| One of EGFR/CXCR1 was high expression | 61 (65.6) | 32 (34.4) | < 0.001b |
| Both EGFR/CXCR1 were high expression | 5 (7.7) | 60 (92.3) | |
| GPER1/EGFR/CXCR1 | |||
| Not all of GPER1/EGFR/CXCR1 was or were high expression | 127 (70.9) | 52 (29.1) | < 0.001c |
| All of GPER1/EGFR/CXCR1 were high expression | 1 (1.8) | 54 (98.2) |
Correlation of concomitant high expression of GPER1, EGFR and CXCR1 with the occurrence of FTC was measured by Chi-square test.
a
Stands for significant difference among the three groups;
b
Stands for significant difference between group (2) and group (3);
c
Stands for significant difference between groups with and without concomitant high expression of all three molecules.
P < 0.05 was considered statistically significant.