Table 1.
The differentially expressed genes related to apoptosis, viral carcinogenesis and from MAPK signaling pathway in CNE-1/Taxol, 5-8F/Taxol and HNE-2/Taxol cells of FOLR1 downregulation
| Gene symbol | Access | Gene description | Fold change (CNE-1/Taxol) | Fold change (5-8F/Taxol) | Fold change (HNE-2/Taxol) |
|---|---|---|---|---|---|
| Apoptosis-related genes | |||||
| BIRC3 | NM_001165 | baculoviral IAP repeat-containing 3 | -2.25 | -2.23 | -7.83 |
| IL1A | NM_000575 | interleukin 1, alpha | -9.25 | -6.41 | -4.37 |
| PRKX | NM_005044 | protein kinase, X-linked | -2.08 | -4.60 | -5.67 |
| TNFRSF10A | NM_003844 | tumor necrosis factor receptor superfamily, member 10a | 2.06 | 2.27 | 5.48 |
| Viral carcinogenesis | |||||
| C3 | NM_000064 | complement component 3 | -4.48 | -3.72 | -3.35 |
| EGR2 | NM_000399 | early growth response 2 | -6.79 | -2.27 | -3.80 |
| IL6ST | NM_001190981 | interleukin 6 signal transducer | -2.10 | -3.23 | -13.41 |
| NRAS | NM_002524 | neuroblastoma RAS viral (v-ras) oncogene homolog | -2.03 | -2.84 | -6.09 |
| PRKX | NM_005044 | protein kinase, X-linked | -2.08 | -4.60 | -5.67 |
| MAPK signaling pathway | |||||
| DUSP1 | NM_004417 | dual specificity phosphatase 1 | -10.32 | -3.55 | -4.42 |
| FOS | NM_005252 | FBJ murine osteosarcoma viral oncogene homolog | -26.81 | -6.26 | -11.10 |
| HSPA1A | NM_005345 | heat shock 70 kDa protein 1A | 10.00 | 2.03 | 5.05 |
| IL1A | NM_000575 | interleukin 1, alpha | -9.25 | -6.41 | -4.37 |
| NRAS | NM_002524 | neuroblastoma RAS viral (v-ras) oncogene homolog | -2.03 | -2.84 | -6.09 |
| PDGFA | NM_002607 | platelet-derived growth factor alpha polypeptide | 2.07 | 5.33 | 6.31 |
| PRKX | NM_005044 | protein kinase, X-linked | -2.08 | -4.60 | -5.67 |