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. 2015 Sep 1;8(9):11414–11420.

Figure 2.

Figure 2

The knockdown of HOTTIP inhibited OS cell proliferation, migration and invasion. A. qRT-PCR revealed that HOTTIP expression was efficiently knocked down by treatment with siR-HOTTIP in MG-63 and HOS cells. B. Suppression of HOTTIP in MG-63 and HOS cells significantly reduced their proliferative capacities, as determined by MTT assay. C. Knockdown of HOTTIP reduced migration capacities of MG-63 and HOS cells, as determined by scratch assay. D. Decreased expression of HOTTIP inhibited invasion abilities of MG-63 and HOS cells, as determined by transwell invasion assay. The data represent the mean ± SD of three independent experiments. *P<0.05.