Table 1.
Correlation between DBC1 expression and clinicopathological variables in 104 Gallbladder carcinomas
| Variables | N | DBC1 expression | P value | |
|---|---|---|---|---|
|
|
||||
| Low | High | |||
| Gender | ||||
| female | 53 | 36 (67.8) | 17 (32.1) | .468 |
| male | 51 | 36 (70.6) | 15 (29.4) | |
| Age | ||||
| < 62 | 44 | 33 (75.0) | 11 (25.0) | .191 |
| > 62 | 60 | 39 (65.0) | 21 (35.0) | |
| Histologic grade | ||||
| Well/Mod | 89 | 58 (65.2) | 31 (34.8) | .022* |
| Poor | 15 | 14 (93.3) | 1 (6.7) | |
| Size | ||||
| < 2.5 cm | 51 | 33 (64.7) | 18 (35.3) | .294 |
| > 2.5 cm | 43 | 31 (72.1) | 12 (27.9) | |
| Primary tumor (T) | ||||
| T1-2 | 69 | 44 (63.8) | 25 (36.2) | .069 |
| T3-4 | 35 | 28 (80.0) | 7 (20.0) | |
| Lymph node metastasis | ||||
| Present | 22 | 19 (86.4) | 3 (13.6) | .040* |
| Absent | 82 | 53 (64.6) | 29 (35.4) | |
| Distant metastasis | ||||
| Present | 13 | 8 (61.5) | 5 (38.5) | .364 |
| Absent | 91 | 64 (70.3) | 27 (29.7) | |
| TNM stage | ||||
| I-II | 50 | 30 (60.0) | 20 (40.0) | .040* |
| III-IV | 54 | 42 (77.8) | 12 (22.2) | |
| Lymphatic invasion | ||||
| Present | 54 | 43 (79.6) | 11 (20.4) | .015* |
| Absent | 50 | 29 (58.0) | 21 (42.0) | |
| Vascular invasion | ||||
| Present | 15 | 9 (60.0) | 6 (40.0) | .29 |
| Absent | 89 | 63 (70.8) | 26 (29.2) | |
| Nerve invasion | ||||
| Present | 24 | 19 (79.2) | 5 (20.8) | .172 |
| Absent | 80 | 53 (66.3) | 27 (33.8) | |
| Surgical margin involvement | ||||
| Present | 9 | 9 (100) | 0 | .031* |
| Absent | 95 | 63 (66.3) | 32 (33.7) | |
| Local recurrence | ||||
| Present | 16 | 10 (62.5) | 6 (37.5) | .359 |
| Absent | 88 | 62 (70.5) | 26 (29.5) | |
NOTE. Values are n (%).
*
Statistically significant by the chi-square test.