Table 1.
Clinical and molecular data of 225 WHO grade II and III gliomas
| Variables | All patients number (%) | IDH mutation positive/all (%) | TERTp mutation positive/all (%) |
|---|---|---|---|
| Age | |||
| Median | 40 | 39 | 44 |
| Mean (±SD) | 40.8±12.2 | 40.9±9.6 | 43.7±11.5 |
| Range | 3-79 | 23-79 | 13-70 |
| Sex | |||
| Male | 140 (62.22) | 91/140 (65) | 35/131 (26.72) |
| Female | 85 (37.78) | 58/85 (68.24) | 26/82 (31.71) |
| Pathology | |||
| II | 163 (72.44) | 123/163 (75.46) | 45/158 (28.48) |
| III | 62 (27.56) | 26/62 (41.93) | 16/55 (35.56) |
| Location | |||
| Frontal | 83 (36.89) | 67/83 (80.72) | 30/81 (37.04) |
| Insular | 13 (5.78) | 10/13 (76.92) | 4/13 (30.77) |
| Temporal | 61 (27.11) | 41/61 (67.21) | 15/53 (28.3) |
| Parietal | 35 (15.56) | 25/35 (71.43) | 9/33 (27.27) |
| O & C | 6 (2.67) | 1/6 (16.67) | 0/6 (0) |
| C & C | 6 (2.67) | 3/6 (50) | 0/6 (0) |
| Midline | 21 (9.33) | 2/21 (9.52) | 2/21 (9.52) |
Abbreviations: O & C, Occipital & Cerebellum; C & C, Corpus callosum & Cingulate gyrus. Frontal including tumors located entirely in frontal lobe; Midline including tumors located entirely in corpus callosum, thalamencephalon, periventricular location, brainstem and thoracic spinal cord; Insular including tumors involved in insular, frontotemporal-insular, temporal-insular and frontal-insular lobe; Temporal including tumors involved in temporal, frontotemporal, tempoparietal, temporal-occipital lobe; Parietal including tumors involved in parietal, frontoparietal, parietal-occipital lobe; O & C including tumors located entirely in occipital lobe and cerebellum; C & C including tumors located entirely in corpus callosum and cingulate gyrus.