Table 2.
Association between IL-10 rs1800896, rs1800871 and rs1800872 polymorphisms and risk of liver cirrhosis
| SNPs | Patients | % | Controls | % | HWE | OR (95% CI) | P value |
|---|---|---|---|---|---|---|---|
| rs1800896 | |||||||
| GG | 125 | 39.31 | 152 | 47.80 | 0.90 | 1.0 (Ref.) | - |
| GA | 141 | 44.34 | 135 | 42.45 | 1.27 (0.90-1.80) | 0.16 | |
| AA | 52 | 16.35 | 31 | 9.75 | 2.04 (1.20-3.50) | 0.005 | |
| GA+AA | 193 | 60.69 | 166 | 52.20 | 1.41 (1.02-1.96) | 0.03 | |
| rs1800871 | |||||||
| TT | 128 | 40.25 | 139 | 43.71 | 0.23 | 1.0 (Ref.) | - |
| CT | 139 | 43.71 | 135 | 42.45 | 1.12 (0.79-1.59) | 0.52 | |
| CC | 51 | 16.04 | 44 | 13.84 | 1.26 (0.77-2.07) | 0.34 | |
| CT+CC | 190 | 59.75 | 179 | 56.29 | 1.15 (0.83-1.60) | 0.38 | |
| rs1800872 | |||||||
| AA | 110 | 34.59 | 122 | 38.36 | 0.65 | 1.0 (Ref.) | - |
| AC | 159 | 40.25 | 153 | 48.11 | 1.15 (0.81-1.64) | 0.41 | |
| CC | 49 | 25.16 | 43 | 13.52 | 1.26 (0.76-2.11) | 0.34 | |
| AC+CC | 208 | 65.41 | 196 | 61.64 | 1.18 (0.84-1.65) | 0.32 |