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Inhibitory effect of Annonaceous acetogenins on expression of MDR1 and MRP1. A. Western blot analysis of protein extracts obtained from BEL-7402/5-FU and HepG2/ADM cells; B. mRNA expressions of MDR1 and MRP1 genes in BEL-7402/5-FU and HepG2/ADM cells. Data presented are means ± SD values, N = 3. Bars indicate SD. Significant differences from control were indicated by P<0.05 (*) and P<0.01 (**).
