Table 3.
Diagnostic values of RFNA and CNB for thyroid malignancy in nodules with final diagnoses (n = 91)
| Diagnostic values | All (n = 91) |
NA (n = 58) |
FOA (n = 33) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| RFNA, % | CNB, % | p value | RFNA, % | CNB, % | p value | RFNA, % | CNB, % | p value | |
| Criteria 1 | |||||||||
| Sensitivity | 22.2 (4/18) | 44.4 (8/18) | 0.125 | 23.1 (3/13) | 53.8 (7/13) | 0.125 | 20 (1/5) | 20 (1/5) | 1 |
| Specificity | 100 (73/73) | 100 (73/73) | 100 (45/45) | 100 (45/45) | 100 (28/28) | 100 (28/28) | |||
| PPV | 100 (4/4) | 100 (4/4) | 100 (3/3) | 100 (7/7) | 100 (1/1) | 100 (1/1) | |||
| NPV | 83.9 (73/87) | 88 (73/83) | 81.8 (45/55) | 88.2 (45/51) | 87.5 (28/32) | 87.5 (28/32) | |||
| Accuracy | 84.6 (77/91) | 89 (81/91) | 82.8 (48/58) | 89.7 (52/58) | 87.9 (29/33) | 87.9 (29/33) | |||
| Criteria 2 | |||||||||
| Sensitivity | 44.4 (8/18) | 83.3 (15/18) | 0.021 | 53.8 (7/13) | 84.6 (11/13) | 0.125 | 20 (1/5) | 80 (4/5) | 0.25 |
| Specificity | 98.6 (73/73) | 97.4 (71/73) | 100 (45/45) | 97.8 (44/45) | 96.4 (27/28) | 96.4 (27/28) | |||
| PPV | 88.9 (8/9) | 88.2 (15/17) | 100 (7/7) | 91.7 (11/12) | 50 (1/2) | 80 (4/5) | |||
| NPV | 87.8 (72/82) | 95.9 (71/74) | 88.2 (45/51) | 95.7 (44/46) | 87.1 (27/31) | 96.4 (27/28) | |||
| Accuracy | 87.9 (80/91) | 95.4 (86/91) | 89.7 (52/58) | 94.8 (55/58) | 84.8 (28/33) | 93.9 (31/33) | |||
Data in parentheses are the raw data for the percentages. Criteria 1 indicates malignant diagnostic results as the criteria for the diagnosis of malignancy. Criteria 2 indicates diagnostic results of FN/SFN, suspicious for malignancy or malignant as the criteria for the diagnosis of malignancy. PPV = Positive predictive value; NPV = negative predictive value.