Table 1.
Variable | Evaluable Allicor Recipients (n=93) | Evaluable Placebo Recipients (n=103) |
---|---|---|
Carotid intima-media thickness, mm | 0.929±0.015 | 0.937±0.015 |
Age, years | 60,4±1,1 | 61,5±0,8 |
Smoking history, n (%) | 30 (32.3) | 32 (31.1) |
Family history, n (%) | 18 (19.4) | 17 (16.5) |
Systolic blood pressure, mm Hg | 133.3±1.3 | 131.9±1.4 |
Diastolic blood pressure, mm Hg | 81.8±0.8 | 81.2±0.9 |
Total cholesterol, mMol/L | 6.14±0.12 | 6.02±0.10 |
Triglycerides, mMol/L | 2.17±0.14 | 2.23±0.12 |
HDL cholesterol, mMol/L | 1.07±0.03 | 1.10±0.03 |
LDL cholesterol, mMol/L | 4.06±0.10 | 3.88±0.09 |
Serum-induced intracellular cholesterol accumulation (serum atherogenicity *), % of control | 156.2±5.1 | 156.4±5.2 |
Serum atherogenicity was determined as described in “Subjects and Methods” section. Total intracellular cholesterol content of control cells cultured without patient’s serum addition was set for 100%. The cholesterol content of cells cultured in the presence of patient’s serum was expressed in % of control cells. The serum that induced statistically significant increase in intracellular cholesterol content as compared to control cells was defined as atherogenic.