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. Author manuscript; available in PMC: 2015 Nov 9.
Published in final edited form as: Recent Pat Cardiovasc Drug Discov. 2013 Apr;8(1):56–66. doi: 10.2174/18722083113079990008

Table 1.

Baseline carotid artery intima-media thickness and demographic, clinical and laboratory characteristics.

Variable Evaluable Allicor Recipients (n=93) Evaluable Placebo Recipients (n=103)
Carotid intima-media thickness, mm 0.929±0.015 0.937±0.015
Age, years 60,4±1,1 61,5±0,8
Smoking history, n (%) 30 (32.3) 32 (31.1)
Family history, n (%) 18 (19.4) 17 (16.5)
Systolic blood pressure, mm Hg 133.3±1.3 131.9±1.4
Diastolic blood pressure, mm Hg 81.8±0.8 81.2±0.9
Total cholesterol, mMol/L 6.14±0.12 6.02±0.10
Triglycerides, mMol/L 2.17±0.14 2.23±0.12
HDL cholesterol, mMol/L 1.07±0.03 1.10±0.03
LDL cholesterol, mMol/L 4.06±0.10 3.88±0.09
Serum-induced intracellular cholesterol accumulation (serum atherogenicity *), % of control 156.2±5.1 156.4±5.2
*

Serum atherogenicity was determined as described in “Subjects and Methods” section. Total intracellular cholesterol content of control cells cultured without patient’s serum addition was set for 100%. The cholesterol content of cells cultured in the presence of patient’s serum was expressed in % of control cells. The serum that induced statistically significant increase in intracellular cholesterol content as compared to control cells was defined as atherogenic.