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. 2015 Sep 3;106(10):1303–1312. doi: 10.1111/cas.12755

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© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Downregulation of DDX5 inhibits non-small-cell lung cancer cell proliferation. (a) H520 and A549 cells were stably infected with RNAi-DDX5 or RNAi-Vector. The expression of DDX5 was analyzed by Western blot. (b) Cell growth curves as determined by MTT assay. (c) Percentage of EdU-positive cells determined by EdU incorporation assay (lower panel) and representative images of EdU staining (upper panel). (d) Effects of downregulation of DDX5 on the clonogenic ability of H520 and A549 cells. *P < 0.05.