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. 2015 Sep 4;106(10):1408–1413. doi: 10.1111/cas.12744

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© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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(a) Loss of E-cadherin expression in PanIN-3 lesions associated with chronic pancreatitis (CP). (b) Intact E-cadherin expression in PanIN-3 lesions with no background of CP. (c) Strong nucleocytoplasmic expression of S100A4 in a PanIN-3 lesion associated with CP. (d) No S100A4 expression in a PanIN-3 lesion without associated CP.