Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 9;15:871. doi: 10.1186/s12885-015-1859-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Acar et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — a SNV frequencies in dinucleotide context. Frequencies are compared between SNVs among all SNVs shared among all 4 samples (n = 842–1059), and SNVs shared among all 3 tumours (n = 428–473). Asterisks indicate which base is mutated; e.g. TpC* stands for TpC- > TpA, TpC- > TpG, or TpC- > TpT. Inset shows the frequency of substitutions in all tumours at TpC* sites. We only consider A or C mutations in either strand and their 5’ nucleotides, following [9]. b Proposed development of the bladder cancer lesion from initiation of transformation to migration of the clonal tumours