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RMSD comparisons between replicates at 500 kb resolution. Comparisons across a range (0.10,0.20,…,1.0) of second stage equi-spaced sampling proportions for reconstructions from primary and replicate human GM12878 B-lymphoblastoid cell line pools [12] at a resolution of 500 kb. The referent reconstruction is based on a proportion of 1.0 for the primary series. Overplotting obscures coincident points at some sampling proportions
