Table II.
Polysomnography Results of Infants with Down Syndrome Seen at the Down Syndrome Program at Riley Hospital for Children, August 2005 to December 2011
| All Infants (n=59)1 | Males (n=32) | Females (n=26) | |
|---|---|---|---|
| Average age at diagnosis (days)2 | 44 ± 48 | 34 ± 37 | 61 ± 57 |
| Total sleep time (minutes) | 150 ± 69 | 149 ± 63 | 151±78 |
| End-tidal CO2 mean (mm Hg) | 44 ± 8 | 46 ± 9 | 42 ± 6 |
| Mean Apnea Hypopnea Index | 19 ± 14 | 20 ±15 | 19 ±14 |
| OSA3 Criteria Not Met | 3 | 2 | 1 |
| Mild OSA (AHI 2–5) | 7 | 3 | 4 |
| Moderate OSA (AHI 6–10) | 9 | 4 | 5 |
| Severe OSA (AHI≥10) | 401 | 22 | 17 |
1
Missing gender for 1 infant that underwent polysomnography.
2
Age corrected for prematurity. Average female age at diagnosis skewed by ten infants in sample diagnosed very late (>100 days). Median female age at diagnosis was 58 days. Median male age at diagnosis was 20 days.
3
Obstructive sleep apnea defined by Apnea Hypopnea Index of 2 or more.