Figure 3.

Poly IC attenuates astrogliosis‐associated overexpression of neurocan. (A) Double staining with antineurocan (yellow) and Hoechst (blue) in astrocytes after oxygen‐glucose deprivation (OGD), OGD and 24 h reperfusion (OGD/R), or OGD/R + 1 or 10 μg/mL Poly IC. Scale bar = 20 μm. (B) Immunoblot analysis of neurocan secretion in conditioned medium of astrocytes (band at 130 kD). Results are expressed as a percentage of control OD value and are from three independent experiments. ^&& P < 0.01 versus control group; ^## P < 0.01 versus OGD/R group.