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Partial nucleotide sequence of the ZEB1 and TCF4 variations in FECD patients. Novel ZEB1 changes identified in the study are shown in panels A to D. The ZEB1 single nucleotide polymorphism (SNP) rs220060 and the TCF4 SNP rs613872 significantly associated with Fuchs endothelial corneal dystrophy (FECD) are shown in panels E and F. P=patient; C=control.
