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EA decreased PGC-1α acetylation in the hippocampus of SAMP8 mice. (A) Lysates of hippocampus were used to immunoprecipitate PGC-1α and Western blotting was performed to detect PGC-1α levels and acetylation. (B) The quantification of the ratio of acetylated to total PGC-1α. The results are expressed as a percentage of the control, which is set at 100%. n=5, * p<0.05 versus Rc group; # p<0.05 versus Pc group.
