Table 3. Additional putative toxin transcripts identified by similarity searches.
| Sequence ID | ORF a /Length(bp) | Signal peptide b | Identification (best matched species) | E-value | Possible venom function |
|---|---|---|---|---|---|
| Unigene6213 | N/307 | U | Toxin TX2(Aurelia aurita) | 2E-06 | Hemolytic activity and pore-forming action |
| Unigene8172 | F/2294 | N | Venom dipeptidyl peptidase 4 isoform X2 (Nasonia vitripennis) | 2E-109 | Endopeptidases |
| Unigene41308 | F/961 | N | Venom toxin-like peptide-6 (Mesobuthus eupeus) | 4E-07 | Unknown |
| Unigene41678 | N/566 | N | Plancitoxin-1-like (Hydra vulgaris) | 5E-59 | Potently hepatotoxic |
| Unigene33521 | N/523 | Y | Plancitoxin-1-like (Hydra vulgaris) | 9E-17 | Potently hepatotoxic |
| Unigene4165 | N/327 | U | Venom protein Ci-120 (Chelonus inanitus) | 6E-30 | Proteoglycan metabolism |
| Unigene49242 | N/330 | N | Venom protein Ci-80a (Chelonus inanitus) | 4E-42 | Peptidase |
| Unigene17029 | F/734 | N | Translationally controlled tumor protein homology, TCTP (Ixodes scapularis) | 3E-23 | Histamine releasing factor |
| Unigene7297 | F/1784 | N | Angiotensin-converting enzyme-like (Hydra vulgaris) | 1E-178 | Releasing vasoconstrictive peptides |
| Unigene29942 | N/231 | U | Endothelin-converting enzyme 1-like (Hydra vulgaris) | 5E-06 | Releasing vasoconstrictive peptides |
| Unigene25995 | N/313 | U | Neprilysin-like (Myotis davidii) | 5E-30 | Endopeptidases and potent neurotoxicity |
| Unigene1506 | N/672 | U | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like (Hydra vulgaris) | 6E-22 | Hemostatic disturbance |
| Unigene21452 | N/1661 | N | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (Zonotrichia albicollis) | 3E-101 | Hemostatic disturbance |
| Unigene28395 | N/221 | U | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Columba livia) | 4E-05 | Hemostatic disturbance |
| Unigene39268 | N/1821 | U | Ectonucleotide pyrophosphatase/phosphodiesterase family member 4-like (Hydra vulgaris) | 6E-73 | Hemostatic disturbance |
| Unigene17070 | F/1758 | Y | Vascular endothelial growth factor A-like (Acyrthosiphon pisum) | 7E-09 | Inducing vasodilation and increasing vascular permeability |
| Unigene17673 | F/1989 | Y | Vascular endothelial growth factor A-like (Hydra vulgaris) | 2E-17 | Inducing vasodilation and increasing vascular permeability |
| Unigene39767 | F/1870 | N | Vascular endothelial growth factor toxin (Lepeophtheirus salmonis) | 2E-06 | Unknown |
| Unigene17310 | F/1239 | Y | Vascular endothelial growth factor D (Crassostrea gigas) | 3E-05 | Unknown |
| Unigene40990 | N/498 | U | Lysosomal acid lipase/cholesteryl ester hydrolase-like (Hydra vulgaris) | 2E-48 | Unknown |
| Unigene17402 | F/2567 | Y | Lysosomal acid lipase/cholesteryl ester hydrolase-like (Hydra vulgaris) | 1E-160 | Unknown |
| Unigene17303 | F/1764 | Y | Lysosomal acid lipase/cholesteryl ester hydrolase-like (Hydra vulgaris) | 5E-147 | Unknown |
| Unigene9684 | N/406 | U | Alkaline phosphatase D domain containing protein (Acanthamoeba castllanii) | 2E-36 | Unknown |
| Unigene41552 | F/1246 | N | Dipeptidyl peptidase 3-like (Saccoglossus kowalevskii) | 3E-97 | Inducing hypotension |
| Unigene8247 | F/1977 | N | Ectonucleoside triphosphate diphosphohydrolase 1 (Falco peregrinus) | 7E-65 | Potential inhibitor of platelet aggregation |
| Unigene19363 | F/1872 | N | Ectonucleoside triphosphate diphosphohydrolase6 (Danio rerio) | 5E-94 | Potential inhibitor of platelet aggregation |
a Full-length and not full-length open reading frames (ORFs) are indicated by “F” and “N”, respectively.
b Transcripts with or without a signal peptide are indicated by “Y” and “N”, respectively; transcripts in which the presence of a signal peptide was unclear are indicated by “U” (Unknown).