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(a) Structure of CC0651 (red) bound to Cdc34 (tan). CC0651 does not interact with the active site cysteine (orange). (b) Structure of CC0651 (red) interacting with ubiquitin bound Cdc34 (yellow). (c) The view from b is rotated to better show position of composite binding interface between Cdc34 and ubiquitin. Derived from PDB code 4MDK (ref. 8).
