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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2015 Aug 29;21(12):2061–2068. doi: 10.1016/j.bbmt.2015.08.030

Table 1.

Criteria for Diagnosis of Engraftment Syndrome

Spitzer Criteria Maiolino Criteria
Requirements 3 Major or 2 Major + 1 Minor Major + 1 Minor
Major Criteria Non-infectious Fever, Skin Rash, or Pulmonary Edema Non-infectious Fever
Minor Criteria Weight Gain, Hepatic Dysfunction, Renal Dysfunction, or Transient Encephalopathy Skin Rash, Pulmonary Infiltrates, or Diarrhea
Timing of Symptoms Relative to Engraftment 4 Days Within ANC 0.5 × 109/L 1 Day Within Neutrophils Present