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Adverse Events
| Adverse Events | Grade 1 |
Grade 2 |
Grade 3 |
Grade 4 |
|---|---|---|---|---|
| Hematological AEs | ||||
| Anemia | 16% | 3% | ||
| Neutropenia | 11% | 5% | ||
| Thrombocytopenia | 8% | |||
| Lymphopenia | 3% | 3% | 3% | |
| Non-Hematological AEs | ||||
| Peripheral neuropathy | 49% | 3% | ||
| AST elevation | 32% | 5% | 3% | |
| ALT elevation | 27% | 11% | ||
| Rash (new) | 24% | 11% | 5% | |
| Muscle weakness | 24% | 5% | ||
| Hypoglycemia | 22% | |||
| Fatigue | 19% | 11% | ||
| Pruritis | 19% | 3% | 3% | |
| Nausea | 16% | 3% | ||
| Abdominal Pain | 11% | 5% | ||
| Creatinine elevated | 3% | |||
| Tumor lysis syndrome | 3% | |||
| Hyperuricemia | 3% | |||
